Maternal serum adiponectin multimers in preeclampsia

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Maternal serum adiponectin multimers in preeclampsia.

OBJECTIVE Obesity, insulin resistance, and dyslipidemia are associated with preeclampsia. Recently, "adipose tissue failure", characterized by dysregulation of adipokine production, has been implicated in the pathophysiology of these metabolic complications. Adiponectin, an insulin-sensitizing, anti-atherogenic, anti-inflammatory and angiogenic adipokine, circulates in oligomeric complexes incl...

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Maternal serum levels of adiponectin in preeclampsia.

BACKGROUND The results of the serum levels of adiponectin in preeclamptic patients are conflicting. OBJECTIVE The aim of the present study was to assess serum levels of adiponectin in women with preeclampsia compared with healthy pregnant women. METHODS A cross-sectional study was designed. The case group consisted of women with preeclampsia (n = 30). The control group consisted of 30 match...

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Maternal serum adiponectin multimers in patients with a small-for-gestational-age newborn.

OBJECTIVE Several mechanisms of disease have been implicated in the pathophysiology of small-for-gestational-age (SGA) including an anti-angiogenic state, and an exaggerated intravascular pro-inflammatory response. Adiponectin plays a role in a wide range of biological activities including those that have been implicated in the pathophysiology SGA. Thus, the aim of this study was to determine i...

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Maternal serum adiponectin at 11-13 weeks of gestation in preeclampsia.

OBJECTIVE To determine whether the maternal serum levels of adiponectin in the first trimester of pregnancy are altered in cases that develop preeclampsia (PE) and whether the levels are related to pregnancy-associated plasma protein-A (PAPP-A) and uterine artery pulsatility index (PI). METHODS Serum adiponectin, PAPP-A and uterine artery PI were measured at 11-13 weeks in 90 cases that devel...

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Adiponectin in severe preeclampsia.

AIMS Adiponectin is an adipokine with insulin-sensitizing, anti-atherogenic, anti-inflammatory and angiogenic properties. The aims of this study were to determine whether maternal plasma adiponectin concentrations differ between patients with severe preeclampsia and those with normal pregnancies, and to explore the relationship between plasma adiponectin and the results of Doppler velocimetry o...

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ژورنال

عنوان ژورنال: Journal of Perinatal Medicine

سال: 2009

ISSN: 1619-3997,0300-5577

DOI: 10.1515/jpm.2009.085